The Biggest Loser video game is a fun and engaging way for players to get in shape and maintain their ideal fitness. Set at The Biggest Loser ranch, players can take The Biggest Loser challenge and compete in 4, 8 or 12 week programs against former contestants from the television show, or workout with a friend to form a support system to see who really is The Biggest Loser. Players will work-out to a series of structured routines with special weekly challenges, weigh-ins and eliminations, or they can even create their own workouts. Workouts include upper, lower and core body exercises, as well as cardio and yoga exercises. Progress is documented on a calendar that keeps track of in-game achievements, upcoming training and weigh-in dates. Players can also receive credit for any progress made while not playing the video game, such as going for a walk or a bike ride.

The video game also features 50 healthy recipes from the BiggestLoserClub.com and The New York Times best-selling book series The Biggest Loser to help users learn how to eat right for optimal weight loss. Throughout the Wii workout program, suggestions and tips from contestants and trainers will also help guide players as they transform their lives via diet and exercise. The video game also features an interactive calorie counter that tracks what players are eating and recommends their daily intake based on individual goals.